European Journal of Medicinal Chemistry p. 51 - 57 (1991)
Update date:2022-08-05
Jaguelin
Robert
Gayral
The two carbons of the epoxide ring of the gem-dicyano epoxides and α-cyano α-ester epoxides act as electrophilic centers when these compounds are reacted with 2-mercaptobenzimidazole. The reaction leads to 2,3-dihydrobenzimidazo[2,1-b]-thiazoles. However, such a reactivity of the epoxides is not observed during their reaction with 2-aminothiazoline. Some of the synthetized compounds showed anthelminthic properties.
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(1991)
