European Journal of Medicinal Chemistry p. 51 - 57 (1991)
Update date:2022-08-05
Jaguelin
Robert
Gayral
The two carbons of the epoxide ring of the gem-dicyano epoxides and α-cyano α-ester epoxides act as electrophilic centers when these compounds are reacted with 2-mercaptobenzimidazole. The reaction leads to 2,3-dihydrobenzimidazo[2,1-b]-thiazoles. However, such a reactivity of the epoxides is not observed during their reaction with 2-aminothiazoline. Some of the synthetized compounds showed anthelminthic properties.
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Doi:10.1021/ol203069p
(2012)Doi:10.1021/ja2098063
(2011)Doi:10.1016/j.bioorg.2012.06.003
(2012)Doi:10.1039/c1cc16126a
(2011)Doi:10.1016/j.ejmech.2011.09.051
(2011)Doi:10.1016/S0040-4039(00)85994-8
(1991)
