Tetrahedron Letters p. 2469 - 2470 (1991)
Update date:2022-09-26
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(±)-2-Piperazinecarboxylic acid is prepared from N-carbethoxy-4-piperidone by α Schmidt rearrangement followed by bromation of the lactam; then α Favorskii rearrangement on the monobromolactam intermediate afforded the desired product.
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(1991)
