Tetrahedron Letters p. 2429 - 2432 (1991)
Update date:2022-08-03
Topics:
Hoffman, Robert V.
Salvador, James M.
A one-flask conversion of cyclic ketones to N-methyl lactams is described. Reaction of the ketone with triethylorthoformate generates an acetal which is reacted in situ with N-(((p-nitrobenzene)sulfonyl)oxy methylamine 2a(CH3NH-OSO2C6H4NO2). Dealkylation of the resulting O-ethyl imidate with sodium iodide gives the lactam. A variety of lactams, including macrocyclic lactams, are produced simply and in good yields.
View MoreTaizhou Green Peptide Trading Co., Ltd.
Contact:--
Address:Room 1501, No71, Yuehe Road, Taizhou City, Zhejiang Province, China
ZHANGJIAGANG FREE TRADE ZONE YONG HAN INTERNATIONAL TRADING CO., LTD(expird)
Contact:86 512 57910558
Address:qianjin M road
Hebei Think-Do Environment Co., Ltd
website:http://www.thinkdo-environment.com
Contact:0311-86510809-
Address:No 6, Shilian Middle Street, Circular Chemical Industry Park
Suzhou Howsine Biological Technology Co.,Ltd(expird)
website:http://www.howsine.com
Contact:86-512-67262751
Address:No 3,Weihua Road ,Suzhou Industrial Park ,Jiangsu ,China.
Zouping Mingxing Chemical Co.,Ltd.
website:http://www.zoutong.com.cn
Contact:86-543-2240068 2240067
Address:428 Daixi Third Road Zouping County Shandong Province China
Doi:10.1016/j.bmc.2011.09.041
(2011)Doi:10.1080/07328303.2011.604453
(2011)Doi:10.1016/j.bmcl.2012.02.039
(2012)Doi:10.1002/hlca.19660490815
(1966)Doi:10.1021/acs.organomet.7b00765
(2017)Doi:10.1039/c1cc15946a
(2011)
