The synthesis of an asparenomycin analog

DOI: 10.1016/S0040-4039(00)74477-7

Source and publish data:

Tetrahedron Letters p. 1023 - 1026 (1991)

Update date:2022-07-30

Topics:

Authors:

Bouthillier, Gilles

Mastalerz, Harold

Menard, Marcel

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Article abstract of DOI:10.1016/S0040-4039(00)74477-7

The synthesis of an analog of the carbapenem antibiotics, the asparenomycins, is described. This analog lacks the methyl group in the 6-alkylidene side chain while a methyl group has been placed at the 1β-position. The key step involved the Lewis acid-cat

Full text of DOI:10.1016/S0040-4039(00)74477-7

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Product name:Sodium; (4R,5R)-6-[2-hydroxy-eth-(E)-ylidene]-4-methyl-7-oxo-3-(pyridin-2-ylmethylsulfanyl)-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylate

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