Synthesis of fluorine and iodine analogues of clorgyline and selective inhibition of monoamine oxidase A

DOI: 10.1248/cpb.39.1038

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1038 - 1040 (1991)

Update date:2022-09-26

Topics:

Authors:

Ohmomo Ohmomo

Hirata Hirata

Murakami

Magata Magata

Tanaka Tanaka

Yokoyama

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Article abstract of DOI:10.1248/cpb.39.1038

A series of fluorine and iodine analogues of clorgyline was synthesized and evaluated for inhibitory potency and selectivity toward monoamine oxidase A (MAO-A). Among them, N-[3-(2,4-dichloro-6-iodophenoxy)propyl]-N-methyl-2-propynylamine (3d), N-[3-(4-ch

Full text of DOI:10.1248/cpb.39.1038

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