Journal of Medicinal Chemistry p. 3058 - 3065 (1991)
Update date:2022-07-30
Topics: Synthesis Receptor Binding N-Substituted CIS Enantiomeric N-<2-(3,4-Dichlorophenyl)ethyl>-2-(1-pyrrolidinyl)cyclohexylamines
Radesca, Lilian
Bowen, Wayne D.
Paolo, Lisa Di
Costa, Brian R. de
N-Alkyl-substituted derivatives of (+)- and (-)-cis-N-<2-(3,4-dichlorophenyl)ethyl>-2-(1-pyrrolidinyl)cyclohexylamine have been synthesized in nine steps in a stereospecific manner starting from cyclohexene oxide.The key step in the reaction sequence invo
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Doi:10.1016/S0040-4020(01)91939-8
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