Stereoselective synthesis of hydroxyethylene dipeptide isostere from sugar

Article abstract of DOI:10.1080/00397919608003563

Regioselective opening of the aziridine ring in the carbohydrate-based precursor led to the stereoselective synthesis of N-Boc-O-benzyl-(4S,5S)-5-amino-4-hydroxy-6-phenylhexanoic acid methyl ester, the hydroxyethylene dipeptide isostere moiety of potent HIV-1 protease inhibitor.

Full text of DOI:10.1080/00397919608003563

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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Stereoselective Synthesis of
Hydroxyethylene Dipeptide
Isostere from Sugar
T K Chakraborty a & K K Gangakhedkar a
a Indian Institute of Chemical Technology ,
Hyderabad, 500 007, India
Published online: 21 Aug 2006.
To cite this article: T K Chakraborty & K K Gangakhedkar (1996) Stereoselective
Synthesis of Hydroxyethylene Dipeptide Isostere from Sugar, Synthetic
Communications: An International Journal for Rapid Communication of Synthetic
Organic Chemistry, 26:11, 2045-2056, DOI: 10.1080/00397919608003563
To link to this article: http://dx.doi.org/10.1080/00397919608003563
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