Synthesis of 4-aryl-1,4-dihydro-3(2H)-isoquinolinones by oxidative cyclization of N-benzylaraylacetamides

DOI: 10.1055/s-1991-26498

Source and publish data:

Synthesis p. 476 - 478 (1991)

Update date:2022-08-03

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Authors:

Venkov Venkov

Vodenicharov

Ivanov Ivanov

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Article abstract of DOI:10.1055/s-1991-26498

4-Aryl-1,4-dihydro-3(2H)-isoquinolinones are obtained by oxidative cyclization of N-benzyl-N-alkylarylacetamides with lead tetraacetate in acetic acid/trifluoroacetic acid.

Full text of DOI:10.1055/s-1991-26498

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Product name:2-(3,4-Dimethoxy-phenyl)-N-(3-methoxy-benzyl)-N-methyl-acetamide

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