Synthetic Applications of N-Aryl-O-acyl Hydroxamic Acids. A Convenient Route to 3-Substituted N-Benzoyl Oxindoles

DOI: 10.1016/S0040-4039(00)78815-0

Source and publish data:

Tetrahedron Letters p. 2671 - 2674 (1991)

Update date:2022-08-02

Topics:

Authors:

Almeida, Paulo S.

Prabhakar, Sundaresan

Lobo, Ana M.

Marcelo-Curto, M. Joao

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Article abstract of DOI:10.1016/S0040-4039(00)78815-0

The enol silylethers of N-acyloxybenzanilides undergo smooth rearrangement to afford o-aminobenzoyl-phenylacetic acids and thence to oxindoles by dehydration.Key words: Oxindole; O-acyl hydroxamic acid; O-silylether; 3,3-rearrangement; cyclisation

Full text of DOI:10.1016/S0040-4039(00)78815-0

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