Asymmetric synthesis of monocyclic β-lactams: Application of imines derived from chiral N-protected α-amino aldehydes in the staudinger reaction

DOI: 10.1016/0040-4039(91)80702-8

Source and publish data:

Tetrahedron Letters p. 3109 - 3110 (1991)

Update date:2022-08-03

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Authors:

Palomo, Claudio

Cossio, Fernando P.

Cuevas, Carmen

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Article abstract of DOI:10.1016/0040-4039(91)80702-8

Imines derived from N,O-diprotected L-serinal upon treatment with acid chlorides in the presence of triethylamine furnished β-lactams with complete level of reaction diastereoselection.

Full text of DOI:10.1016/0040-4039(91)80702-8

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