Synthesis of functionalized long-chain perfluoroalkanes from methyl halodifluoroacetates: a process of difluorocarbene insertion into copper-carbon bonds

Article abstract of DOI:10.1016/S0022-1139(00)80465-0

Treatment of XCF2CO2Me (X = Cl, Br) with organic halides in the presence of KF and catalytic amounts of CuI at 80-120 deg C for 3-8 h in DMF gave long-chain perfluoroalkylated compounds which are considered to be former by the insertions of CF2(..) into carbon-copper bonds.