Journal of Medicinal Chemistry p. 2562 - 2572 (1992)
Update date:2022-08-04
Topics:
Patt, William C.
Hamilton, Harriet W.
Taylor, Michael D.
Ryan, Michael J.
Taylor, David G.
et al.
A series of renin inhibitors was synthesized that contained a 2-amino-4-thiazolyl moiety at the P2 position.These derivatives are potent inhibitors of monkey renin in vitro and are selective in that they only weakly inhibit the closely related
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