Catalytic enantioselective arylation of aldehydes by using functionalized grignard reagents generated from aryl bromides

DOI: 10.1055/s-0031-1289854

Source and publish data:

Synlett p. 2875 - 2879 (2011)

Update date:2022-09-26

Topics:

Authors:

Itakura, Daisuke

Harada, Toshiro

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Article abstract of DOI:10.1055/s-0031-1289854

An efficient catalytic method has been developed for the enantioselective synthesis of functionalized diarylmethanols starting from aryl bromides and aldehydes. In the presence of (R)-3-(3,5-diphenylphenyl)BINOL (2 mol%) and titanium tetraisopropoxide, fu

Full text of DOI:10.1055/s-0031-1289854

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