Journal of Organic Chemistry p. 5739 - 5740 (1991)
Update date:2022-07-30
Topics:
Turner, Richard M.
Lindell, Stephen D.
Ley, Steven V.
Treatment of N-protected 4-iodoimidazoles 1-3 in CH2Cl2 solution with an etheral solution of ethylmagnesium bromide generates the corresponding imidazol-4-yl anions, which react with carbonyl compounds to give carbinols 4-14 in 60-83percent yield.
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