Highly Stereoselective SE' Additions of α-Alkoxy Allylstannanes to Chiral Aldehydes. Synthesis of a C-1-C-9 Subunit of Tylonolide

Article abstract of DOI:10.1021/jo00019a003

The racemic α-alkoxy allylic stannane RS4 adds to the 2S aldehyde 24 to afford the homoaldol adduct 25 (45percent) derived exclusively from the S enantiomer S4 along with isomerized (R)-γ-alkoxy allylstannane 26 of >80percentee (50percent) and unreacted a