Reactivity of β-(trifluoromethyl) acroleins towards primary alkyl (or aryl) amines: synthesis of trifluoromethyl)-1-aza-1,3-dienes and secondary (trifluoromethyl) allylamines

Article abstract of DOI:10.1016/0022-1139(94)03166-W

Vilsmeier's reaction on trifluoroketones leads to β-chloro-β(trifluoromethyl)acroleins.The addition of primary alkyl- or aryl-amines to these acroleins leads in all cases to the formation of stable (trifluoromethyl)-1-aza-1,3-dienes which can be transform