Synthesis and Biological activity of new HMG-CoA reductase inhibitors. 3.1,2 lactones of 6-phenoxy-3,5-dihydroxyhexanoic acids

DOI: 10.1021/jm00114a004

Source and publish data:

Journal of Medicinal Chemistry p. 2962 - 2983 (1991)

Update date:2022-08-03

Topics:

Authors:

Jendralla

Granzer Granzer

V Kerekjarto

Krause Krause

Schacht Schacht

Baader Baader

Bartmann

Beck Beck

Bergmann

Kessler Kessler

Wess Wess

Chen Chen

Granata Granata

Herchen Herchen

Kleine Kleine

Schussler

Wagner Wagner

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00114a004

A group of 43 optically active sodium carboxylates (11a-qq and the corresponding lactones 4 were prepared from respective phenols 8 according to Schemes I-III. Phenols 8 were synthesized from commercially available compounds according to Schemes IV-IX. A

Full text of DOI:10.1021/jm00114a004

Products guided by the article

Product name:3-(cyclohexylmethyl)-5-isopropyl-4-nitrobiphenyl

Cas No:136007-92-6

R&D Labs maybe for 136007-92-6

Tianjin Tongde Biological Technology Co., Ltd.

Contact:86-22-23309138

Address:Room 402, bulidingE3 Detection certification park, XiQingDistrict, Tianjin City
Chiral Quest (Suzhou) Company Ltd

website:http://www.chiralquest.com

Contact:+86-0512-62956066

Address:B1/9, 218 Xinghu Street, Suzhou Industrial Park
Shanghai Cheerchem Co., Ltd.

Contact:86-21-50966856

Address:Building 5,300 Chuanzhan Road,Pudong New District,Shanghai
Shanghai chemrole co.,ltd

Contact:021-50278900

Address:No.6,Room 201 ,Lane 299,bisheng road ,shanghai ,china
TIANJIN ZHONGXIN CHEMTECH CO.,LTD.

Contact:86-022-66880623

Address:FINANCIAL STREET WEST BLK 7, #308, NO.52 XINCHENG WEST ROAD, TEDA, TIANJIN, P.R.CHINA

Relevant to this article

Combining photo-redox and enzyme catalysis for the synthesis of 4H-pyrimido[2,1-b] benzothiazole derivatives in one pot

Doi:10.1016/j.bioorg.2020.104534
(2021)
Rhodium-catalyzed annulation of N-benzoylsulfonamide with isocyanide through C-H activation

Doi:10.1002/chem.201102475
(2011)
Synthesis and antimalarial and antituberculosis activities of a series of natural and unnatural 4-methoxy-6-styryl-pyran-2-ones, dihydro analogues and photo-dimers

Doi:10.1016/j.bmc.2011.12.053
(2012)
4-Aminoquinoline-chalcone/-N-acetylpyrazoline conjugates: Synthesis and antiplasmodial evaluation

Doi:10.1016/j.ejmech.2017.07.041
(2017)
Synthesis of functionalized nitroalkanes by oxidation of oximes with urea-hydrogen peroxide complex and trifluoroacetic anhydride

Doi:10.1016/S0040-4039(00)61298-4
(1992)
Reactivity of dipyridyl ditellurides with (diphosphine)Pt⁰ and 2-pyridyltellurolates with (diphosphine)PtCl₂ and isolation of different structural motifs of platinum(II) complexes

Doi:10.1021/om2010589
(2012)

Article Doi