Synthesis and Biological activity of new HMG-CoA reductase inhibitors. 3.1,2 lactones of 6-phenoxy-3,5-dihydroxyhexanoic acids

DOI: 10.1021/jm00114a004

Source and publish data:

Journal of Medicinal Chemistry p. 2962 - 2983 (1991)

Update date:2022-08-03

Topics:

Authors:

Jendralla

Granzer Granzer

V Kerekjarto

Krause Krause

Schacht Schacht

Baader Baader

Bartmann

Beck Beck

Bergmann

Kessler Kessler

Wess Wess

Chen Chen

Granata Granata

Herchen Herchen

Kleine Kleine

Schussler

Wagner Wagner

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00114a004

A group of 43 optically active sodium carboxylates (11a-qq and the corresponding lactones 4 were prepared from respective phenols 8 according to Schemes I-III. Phenols 8 were synthesized from commercially available compounds according to Schemes IV-IX. A

Full text of DOI:10.1021/jm00114a004

Products guided by the article

Product name:3-(cyclohexylmethyl)-5-isopropyl-4-nitrobiphenyl

Cas No:136007-92-6

R&D Labs maybe for 136007-92-6

NIGNXIA XINDACHANG TECHNOLOGY CO.,LTD

Contact:86-0951-7815345

Address:North side of Qiyuan Road, west side of Yuanfeng Highway, New Material Park, Ningdong Energy and Chemical Industry Base, Ningxia,China
Hangzhou Chemfar Ltd.

Contact:+86-571-87859231, 87859237, 87859239

Address:1606,Huarong Times Mansion, No.3880 Jiangnan Avenue, Binjiang District, Hangzhou, China, 310053
Chuzhou Baiao Biologhy S&T Co., Ltd.

Contact:+86-25-83212599；+86-25-83212699 13705185959

Address:Room 905, Tianzheng International Platza, No.399, Zhongyang Road ,Nanjing, Jiangsu Province, China
Dongying J&M Chemical Co., Ltd,

Contact:546-8551108

Address:Room 1219, Zisheng Mansion, Zibo Road, Dongying, Shandong, China
Nanjing Samwon International Limited

Contact:+86-25-84873444

Address:1108, BLDG B, New Century Plaza, No 1, South Taiping Rd.,

Relevant to this article

Combining photo-redox and enzyme catalysis for the synthesis of 4H-pyrimido[2,1-b] benzothiazole derivatives in one pot

Doi:10.1016/j.bioorg.2020.104534
(2021)
Rhodium-catalyzed annulation of N-benzoylsulfonamide with isocyanide through C-H activation

Doi:10.1002/chem.201102475
(2011)
Synthesis and antimalarial and antituberculosis activities of a series of natural and unnatural 4-methoxy-6-styryl-pyran-2-ones, dihydro analogues and photo-dimers

Doi:10.1016/j.bmc.2011.12.053
(2012)
4-Aminoquinoline-chalcone/-N-acetylpyrazoline conjugates: Synthesis and antiplasmodial evaluation

Doi:10.1016/j.ejmech.2017.07.041
(2017)
Synthesis of functionalized nitroalkanes by oxidation of oximes with urea-hydrogen peroxide complex and trifluoroacetic anhydride

Doi:10.1016/S0040-4039(00)61298-4
(1992)
Reactivity of dipyridyl ditellurides with (diphosphine)Pt⁰ and 2-pyridyltellurolates with (diphosphine)PtCl₂ and isolation of different structural motifs of platinum(II) complexes

Doi:10.1021/om2010589
(2012)

Article Doi