Journal of Organic Chemistry p. 6864 - 6869 (2015)
Update date:2022-08-06
Topics:
Netz, Isabelle
Kucukdisli, Murat
Opatz, Till
A series of α-quaternary arylglycines were prepared in high optical purity (up to 98% ee) by α-alkylation of deprotonated α-aminonitriles derived by the Strecker reaction from (4S,5S)-5-amino-2,2-dimethyl-4-phenyl-1,3-dioxane. The procedure includes only chromatographic purification of the final products and is devoid of chromatography or crystallization operations on intermediates to raise the optical purity.
View MoreShijiazhuang Haitian Amino Acid Co., Ltd.
Contact:+86-311-88908111
Address:Shijiazhuang Hebei province,China
Tangshan Wisdom Trading Co.,Ltd
Contact:86 315 2222979
Address:No.41 BeiXinXi Road, Yangguang building 1-1102 , Tangshan, Hebei, China
Nanjing Samwon International Limited
Contact:+86-25-84873444
Address:1108, BLDG B, New Century Plaza, No 1, South Taiping Rd.,
Shanghai Chemchallenger Biotech Co., Ltd.
Contact:0086-21-68110815
Address:Room 2056, Building 1, No. 1065, Jiaxin Road Shanghai China (Mainland) 201800
Contact:+852-8198 2399
Address:9E, Leapont Industrial Building, 18-28 Wo Liu Hang Road, Shatin, New Territories, Hong Kong
Doi:10.1002/anie.201105812
(2011)Doi:10.1039/c1dt11716e
(2012)Doi:10.1246/cl.130275
(2013)Doi:10.1002/chem.201102059
(2012)Doi:10.1016/j.jfluchem.2011.10.008
(2012)Doi:10.1002/anie.201107104
(2012)