Synthesis of novel isothiazole and isothiazolo[4,5-d] pyrimidine analogues of the natural C-nucleosides pyrazofurin and the formycins

Article abstract of DOI:10.1080/15257779408013275

The cycloaddition of tri-O-benzyl-2,5-anhydro-D-allononitrile-N-sulfide with dimethyl acetylenedicarboxylate or with dimethyl fumarate followed by DDQ oxidation was found to give the benzoyl protected dimethyl 3-β-D- ribofuranosyl-isothiazoledicarboxylate

Full text of DOI:10.1080/15257779408013275

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Nucleosides and Nucleotides
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Synthesis of Novel Isothiazole and
Isothiazolo[4,5-d] Pyrimidine Analogues
of the Natural C-Nucleosides Pyrazofurin
and the Formycins
Diederik K. Buffel a , Lieven Meerpoel a , Suzanne M. Toppet a &
Georges J. Hoornaert a
a Laboratorium voor Organische synthese, Departement Scheikunde ,
Katholieke Universiteit Leuven , Celestijnenlaan 200F, B-3001,
Heverlee-Leuven, Belgium
Published online: 23 Sep 2006.
To cite this article: Diederik K. Buffel , Lieven Meerpoel , Suzanne M. Toppet & Georges J. Hoornaert
(1994) Synthesis of Novel Isothiazole and Isothiazolo[4,5-d] Pyrimidine Analogues of the Natural
C-Nucleosides Pyrazofurin and the Formycins, Nucleosides and Nucleotides, 13:1-3, 719-736, DOI:
10.1080/15257779408013275
To link to this article: http://dx.doi.org/10.1080/15257779408013275
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