Synthesis of novel isothiazole and isothiazolo[4,5-d] pyrimidine analogues of the natural C-nucleosides pyrazofurin and the formycins

DOI: 10.1080/15257779408013275

Source and publish data:

Nucleosides and Nucleotides p. 719 - 736 (1994)

Update date:2022-07-30

Topics:

Authors:

Buffel Buffel

Meerpoel

Toppet Toppet

Hoornaert

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Article abstract of DOI:10.1080/15257779408013275

The cycloaddition of tri-O-benzyl-2,5-anhydro-D-allononitrile-N-sulfide with dimethyl acetylenedicarboxylate or with dimethyl fumarate followed by DDQ oxidation was found to give the benzoyl protected dimethyl 3-β-D- ribofuranosyl-isothiazoledicarboxylate

Full text of DOI:10.1080/15257779408013275

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Product name:dimethyl 3-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-4,5-isothiazoledicarboxylate

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