Studies on the asymmetric Birch reductive alkylation to access spiroimines

DOI: 10.1016/j.tetlet.2012.01.008

Source and publish data:

Tetrahedron Letters p. 1370 - 1372 (2012)

Update date:2022-07-30

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Authors:

Jousseaume, Thierry

Retailleau, Pascal

Chabaud, Laurent

Guillou, Catherine

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Article abstract of DOI:10.1016/j.tetlet.2012.01.008

The asymmetric Birch reductive alkylation has been investigated to synthesize spiroimine analogs of the neurophycotoxin (-)-gymnodimine A 1. Two types of chiral aromatic substrates, an acyclic benzamide 2 and a benzoxazepinone 3 were studied. We found tha

Full text of DOI:10.1016/j.tetlet.2012.01.008

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