The Use of 3-Alkyl-2,4-Diketopiperidines in Asymmetric Michael Additions

DOI: 10.1016/S0957-4166(00)82163-1

Source and publish data:

Tetrahedron Asymmetry p. 407 - 410 (1991)

Update date:2022-07-30

Topics:

Authors:

Ambroise, Lydia

Chassagnard, Claude

Revial, Gilbert

d'Angelo, Jean

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Article abstract of DOI:10.1016/S0957-4166(00)82163-1

Chiral enamine 12, derived from 2,4-diketopiperidine 11 added to methyl acrylate, leading, after hydrolytic work-up to adduct 15 (94percent stereoselectivity).

Full text of DOI:10.1016/S0957-4166(00)82163-1

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