Synthesis and antibacterial activity of new tetracyclic quinolone antibacterials

DOI: 10.1021/jm00079a011

Source and publish data:

Journal of Medicinal Chemistry p. 94 - 99 (1992)

Update date:2022-08-05

Topics:

Authors:

Taguchi Taguchi

Kondo Kondo

Inoue Inoue

Kawahata

Jinbo Jinbo

Sakamoto

Tsukamoto

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Article abstract of DOI:10.1021/jm00079a011

A series of 8-substituted-9,1-(epoxymethano)-7-fluoro-5-oxo-5H- thiazolo[3,2-a]quinoline-4-carboxylic acids having a novel tetracyclic structure was synthesized and tested for antibacterial activity. The nature of the heteroatom (N, O, or S) substituted a

Full text of DOI:10.1021/jm00079a011

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