An improved procedure for the preparation of alkyl N-(4-aryl-2-thiazolyl)oxamates

DOI: 10.1055/s-1991-26569

Source and publish data:

Synthesis p. 763 - 764 (1991)

Update date:2022-07-30

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Lesimple

Bigg Bigg

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Article abstract of DOI:10.1055/s-1991-26569

2-Amino-4-arylthiazoles react cleanly with dialkyl oxalates in the presence of sodium alkoxides at room temperature to afford alkyl N-(4-aryl-2-thiazolyl)oxamates in high yield.

Full text of DOI:10.1055/s-1991-26569

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Product name:N-[4-(4-Methoxy-phenyl)-thiazol-2-yl]-oxalamic acid butyl ester

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