
Journal of the Chemical Society. Chemical communications p. 875 - 877 (1991)
Update date:2022-08-04
Topics:
Freeman, Sally
Irwin, William J.
Mitchell, Antony G.
Nicholls, Dave
Thomson, William
In contrast to high chemical stability (t1/2 55.4 h at 36.4 deg C), with porcine liver carboxyesterase the title compound 1 spontaneously decomposes first to the monoester 2 then to methylphosphonate, both reactions proceeding via the 4-hydroxybenzyl intermediates 3 and 4.
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