Total Synthesis of Griseolic Acid Derivatives from D-Glucose

DOI: 10.1021/jo00024a022

Source and publish data:

Journal of Organic Chemistry p. 6819 - 6822 (1991)

Update date:2022-08-04

Topics:

Authors:

Tulshian, Deen

Doll, Ronald J.

Stansberry, Mary F.

McPhail, Andrew T.

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Article abstract of DOI:10.1021/jo00024a022

Griseolic acid, 1, is a potent nonselective cyclic nucleotide-phosphodiesterase inhibitor isolated from Streptomyces griseoaurantiacus.Recently, preparation of several griseolic acid derivatives, including 3, has been reported.We have completed the chiral

Full text of DOI:10.1021/jo00024a022

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