
Tetrahedron Letters p. 3863 - 3866 (1991)
Update date:2022-08-05
Topics:
Harnden, Michael R.
Jarvest, Richard L.
The synthesis is described of the first members of a new class of nucleoside analogues in which the tetrahydrofuran ring is replaced by a pyrrolidine ring linked to the base through an N-N bond: the pyrrolidinyl analogues of 2',3'-dideoxycytidine (10), uridine (8), and thymidine (9) were prepared via construction of the base on a 1-aminopyrrolidine (15).
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Doi:10.1016/0040-4039(91)80044-7
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