Payne rearrangement route to the optically active oxirane precursor for the preparation of triazole antifungals

DOI: 10.1248/cpb.40.562

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 562 - 564 (1992)

Update date:2022-07-29

Topics:

Authors:

Konosu Konosu

Miyaoka Miyaoka

Tajima Tajima

Oida Oida

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.40.562

Optically active epoxide 1, an important intermediate for the preparation of antifungal triazole-amides 2, was synthesized starting from the (S)-lactic acid-derived ketone 9 and taking advantage of the Payne rearrangement of the epoxyalcohol 8.

Full text of DOI:10.1248/cpb.40.562

NII-Electronic Library Service

Products guided by the article

Product name:(2R,3R)-2-(2,4-Difluoro-phenyl)-3-methyl-2-vinyl-oxirane

Cas No:137035-04-2

R&D Labs maybe for 137035-04-2

Changsha Yonta Industry Co., Ltd.

Contact:+ 86-731-8535 2228

Address:Rm.1717, North Bldg., No.368, East 2nd Ring Road(2nd Section)
Taizhou Sunny Chemical Co.,Ltd

Contact:+86-523-86920899 +86-13951172783

Address:No.11 Xingyuang road, Gaoyong Chemical Industry Park, Gaogang Jiangsu China
Jinan Hongfangde Pharmatech Co.LTD

Contact:0531-88870908

Address:F Bldg,750#,Shunhua Rd,New&High-tech Zone,Jinan,Shandong,China 250101
Tianjin Hedong Red Cliff Chemical Reagent Factory

Contact:+86-022-84780548

Address:Li Ming Zhuang Gong Ye Yuan,Dongli District,Tianjin,China
Zhejiang Sucon Silicone Co.,Ltd

Contact:+86-575-88046692

Address:Qisheng Rd., Paojiang Industrial Zone, Shaoxing, Zhejiang, China.

Relevant to this article

Doi:10.1021/ja01120a509
(1953)
Doi:10.1097/00005537-200211000-00008
(1955)
Nondirected, cu-catalyzed sp³ C-H aminations with hydroxylamine-based amination reagents: Catalytic and mechanistic studies

Doi:10.1021/acs.organomet.7b00003
(2017)
Conversion of serine to stereochemically pure β-substituted α-amino acids via β-lactones

Doi:10.1021/ja00310a058
(1985)
Synthesis of diarylmethanes via metal-free reductive cross-coupling of diarylborinic acids with tosyl hydrazones

Doi:10.1021/jo302207b
(2012)
ON THE CHEMISTRY OF LITHIUM DIALLYL CUPRATE

Doi:10.1016/S0040-4039(00)84277-X
(1986)

Article Doi