Design and synthesis of new potential photoaffinity labels for mammalian squalene epoxidase

DOI: 10.1016/S0960-894X(97)00175-3

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1153 - 1156 (1997)

Update date:2022-08-03

Topics:

Authors:

Gotteland

Dax Dax

Halazy Halazy

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(97)00175-3

Aromatic azides derived from known inhibitors have been prepared as potential photoaffinity labels for mammalian squalene epoxidase. Three of them (compounds 5b, 5c and 6) were found to inhibit pig liver SE with submicromolar affinities and to block cholesterol biosynthesis in HepG2 cells.

Full text of DOI:10.1016/S0960-894X(97)00175-3

Products guided by the article

Product name:3-([3,3']Bithiophenyl-5-ylmethoxy)-benzaldehyde

Cas No:137320-60-6

R&D Labs maybe for 137320-60-6

Qingdao Pana-Life Biochem Co.,Ltd.

Contact:86-532-87683902

Address:No.967 Dalao Road, Licang Zone, Qingdao City,Shandong, China 266021
Hunan Haili Chemical Industry Co.,Ltd.

Contact:+86-731-85521860

Address:No.251, 2nd Section, Furong Road, Changsha,Hunan,China
zhenjiang runjing high purity chemical co ltd

Contact:+86-511-83361155

Address:No.8.haixi road,international chemical park
DU-HOPE INTERNATIONAL GROUP

Contact:+86-25-52346955

Address:199,JIANYE ROAD,NANJING,CHINA
Changzhou BaoKang Pharmaceutical & Chemical Co., Ltd

Contact:(86) 519-88782201 88784080 88785278

Address:Henglin town, changzhou,Jiangsu

Relevant to this article

Copper-Photocatalyzed Hydrosilylation of Alkynes and Alkenes under Continuous Flow

Doi:10.1002/chem.202101753
(2021)
Magnesium-catalysed hydroboration of aldehydes and ketones

Doi:10.1039/c2cc30565h
(2012)
Structural characterization of new compound from the ring-opening reaction of 3-(1H-1,2,4-triazol-1-yl)-1,5-benzothiazepine with phenylonitrile oxide

Doi:10.1007/s10870-010-9911-7
(2011)
Friedel-crafts alkylation of indoles with nitroalkenes catalyzed by Zn(II)-thiourea complex

Doi:10.1002/cjoc.201180480
(2012)
Synthesis of new pyrazole, triazole, and thiazolidine-pyrimido [4, 5-b] quinoline derivatives with potential antitumor activity

Doi:10.1007/s12272-012-0306-5
(2012)
Supramolecular displacement-mediated activation of a silent fluorescence probe for label-free ligand screening

Doi:10.1021/ja301204z
(2012)

Article Doi