DESIGN AND SYNTHESIS OF NEW FLUOROGENIC HIV PROTEASE SUBSTRATES BASED ON RESONANCE ENERGY TRANSFER

DOI: 10.1016/S0040-4039(00)97099-0

Source and publish data:

Tetrahedron Letters p. 6493 - 6496 (1990)

Update date:2022-08-04

Topics:

Authors:

Wang, Gary T.

Matayoshi, Edmund

Huffaker, H. Jan

Krafft, Grant A.

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Article abstract of DOI:10.1016/S0040-4039(00)97099-0

The design and synthesis of new fluorogenic substrate probes for HIV protease based on resonance energy transfer are described.These substrates permit sensitive, continuous measurement of HIV protease activity.

Full text of DOI:10.1016/S0040-4039(00)97099-0

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