Highly selective formation of β-glycosides of N-acetylglucosamine using catalytic iron(III) Triflate

Article abstract of DOI:10.1002/ejoc.201200062

Efficient and highly selective glycosylation reactions of peracetylated β-D-N-acetylglucosamine are described using catalytic iron(III) triflate and 2,4,6-tri-tert-butylpyrimidine (TTBP) under microwave conditions. We have demonstrated that the formation of β-(1→6) and β-(1→3) linked disaccharides are obtained in high yields in the presence ofvarious protecting groups.