Synthesis and evaluation of 2-[2-(phenylthiomethyl)-1H-benzo[d] imidazol-1-yl)acetohydrazide derivatives as antitumor agents

DOI: 10.1016/j.bmcl.2012.03.061

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 3122 - 3125 (2012)

Update date:2022-08-06

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Authors:

Liu, Ting

Sun, Changyan

Xing, Xiumei

Jing, Lingling

Tan, Rui

Luo, Youfu

Huang, Wencai

Song, Hang

Li, Zicheng

Zhao, Yinglan

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Article abstract of DOI:10.1016/j.bmcl.2012.03.061

A novel class of acetylhydrazone derivatives (5a-x) containing 2-(phenylthiomethyl)-1H-benzo-[d]-imidazole moieties are synthesizer, and their antitumor activities against A549, HCT116, HepG2, PC-9, and A375 were determined by the MTT assay. Among them ar

Full text of DOI:10.1016/j.bmcl.2012.03.061

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Product name:tert-butyl 2-(2-(phenylthiomethyl)-1H-benzo[d]imidazol-1-yl)acetate

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