Synthesis, Antinociceptive Activity, and Opioid Receptor Profiles of Substituted trans-3-(Decahydro- and Octahydro-4a-isoquinolinyl)phenols

DOI: 10.1021/jm00079a005

Source and publish data:

Journal of Medicinal Chemistry p. 48 - 56 (1992)

Update date:2022-08-03

Topics:

Authors:

Judd, Duncan B.

Brown, Dearg S.

Lloyd, Jane E.

McElroy, Andrew B.

Scopes, David I. C.

et al. et al.

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Article abstract of DOI:10.1021/jm00079a005

A series of trans-3-(6- and 7-substituted-decahydro-4a-isoquinolinyl)phenols and trans-3-(octahydro-4a-isoquinolinyl)phenols have been synthesized as potential opioid analgesics.Using a combination of in vitro and in vivo test systems, the receptor profil

Full text of DOI:10.1021/jm00079a005

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Product name:ethenyl (+/-)-trans-3,4,4a,5,8,8a-hexahydro-4a-(3-methoxyphenyl)-2(1H)-isoquinolinecarboxylate

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