Palladium-catalyzed reactions in aqueous media. An efficient removal of allyloxycarbonyl protecting group from oxygen and nitrogen

Article abstract of DOI:10.1016/S0040-4039(00)60524-5

The Allyloxycarbonyl (Alloc) moiety can be removed smoothly and selectively in good yield (70-99%) from allylic esters, carbamates and carbonates by aqueous Pd (0) catalyzed allyl transfer to diethylamine as the accepting nucleophile. The method has been successfully used for deprotection of a wide range of secondary amines.