Unexpected MIMIRC Annulation Between a Lithium Dienolate and Methyl Acrylate

DOI: 10.1016/0040-4039(91)80076-I

Source and publish data:

Tetrahedron Letters p. 5531 - 5534 (1991)

Update date:2022-07-29

Topics:

Authors:

Jaafar, Akram

Alilou, El Houssine

Reglier, Marius

Waegell, Bernard

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(91)80076-I

We describe an unusual <2+2+2> MIMIRC reaction between a lithium dienolate 6 and methyl acrylate.The more classical double Michael addition cyclisation provides an efficient entry towards key intermediate 5 for 2-isocyanopupukeanane 1 synthesis.

Full text of DOI:10.1016/0040-4039(91)80076-I

Products guided by the article

Product name:(1S,6S,8R,11S)-2,6-Dimethyl-9-oxo-10-oxa-tricyclo[6.2.2.0^1,6]dodec-2-ene-11-carboxylic acid methyl ester

Cas No:137762-21-1

R&D Labs maybe for 137762-21-1

Jiangsu King Road New Materials Co., Ltd.

website:http://www.jskingroad.com

Contact:0519-85720726 0519-85720721 15006126856

Address:No.1,Weihua Road,Xinbei District,Changzhou City,Jiangsu Province
Guangzhou Puho Pharmaceutical Technology Co. Ltd.

Contact:86-20-29848035/29848075

Address:No.166, Chaoyang East Road, Panyu District, Guangzhou City, Guangdong Province
Huangshi Shennong Chemical Technology Co., Ltd

Contact:+86-714-3072290

Address:Eastern industrial park , Tieshan district , Huangshi city ,Hubei province , China
Tai zhou world Pharm & Chem Co., Ltd

Contact:+86-576-85301198

Address:Rome 1001,wangjiang plaza,unti 2,jinshan east Road linhai,zhejiang,china
Changzhou Qidi Chemical Co., Ltd

website:http://www.czqdhg.com/

Contact:86-519-83382137

Address:128-1-16# HuaYuan Street,Hutang Town,Wujin District,Changzhou City,P.R.China.

Relevant to this article

Vascular barrier protective effects of eckol and its derivatives

Doi:10.1016/j.bmcl.2012.04.026
(2012)
Highly efficient one-pot, three-component synthesis of β-aminoketones catalyzed by Fe(O₂CCF₃)₃

Doi:10.1080/00397911.2011.569866
(2012)
Ionic liquid-mediated facile synthesis and antimicrobial study of thiazolo [2,3-b]benzo[h]quinazolines and thiazino[2,3-b] benzo-[h]quinazolines

Doi:10.1080/10426507.2011.647145
(2012)
A general method for detecting protease activity via gelation and its application to artificial clotting

Doi:10.1039/c2cc31537h
(2012)
Gold-catalysed oxyarylation of styrenes and mono- and gem-disubstituted olefins facilitated by an iodine(III) oxidant

Doi:10.1002/chem.201103061
(2012)
Lanthanide complexes combined with chiral salen ligands: Application in the enantioselective epoxidation reaction of α,β-unsaturated ketones

Doi:10.1039/c9ra01529a
(2019)

Article Doi