Pyrimido[1,6-a]benzimidazoles: A new class of DNA gyrase inhibitors

DOI: 10.1021/jm00086a006

Source and publish data:

Journal of Medicinal Chemistry p. 1385 - 1392 (1992)

Update date:2022-08-02

Topics:

Authors:

Hubschwerlen

Pflieger

Specklin

Gubernator

Gmunder Gmunder

Angehrn Angehrn

Kompis Kompis

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Article abstract of DOI:10.1021/jm00086a006

Substituted 4-quinolone- (1, A = CH) and 1,8-naphthyrid-4-one- (1, A = N) 3-carboxylic acids are currently the only classes of clinically useful antibacterial agents exerting their activity by inhibiting the subunit A of DNA gyrase. Pyrimido[1,6-a]benzimi

Full text of DOI:10.1021/jm00086a006

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