Chemical and Pharmaceutical Bulletin p. 1617 - 1630 (1994)
Update date:2022-08-04
Topics: Synthesis Mass spectrometry Derivatives ANGIOTENSIN II NMR (nuclear magnetic resonance) pyrazole FT-IR (Fourier Transform Infrared Spectroscopy) HPLC (High Performance Liquid Chromatography) C-linked Receptor antagonist
Nicolai
Cure
Goyard
Kirchner
Teulon
Versigny
Cazes
Virone-Oddos
Caussade
Cloarec
The synthesis and pharmacological activity of new nonpeptide angiotensin II (AII) receptor antagonists are presented. These 5-O-substituted and 5-C-substituted 3-alkylpyrazole derivatives represent a new series of antagonists and have led to the discovery
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