Journal of the American Chemical Society p. 9078 - 9081 (2012)
Update date:2022-07-30
Topics:
Gati, Wafa
Rammah, Mohamed M.
Rammah, Mohamed B.
Couty, Francois
Evano, Gwilherm
An efficient and general method for the synthesis of 1,4-dihydropyridines and pyridines based on a lithiation/isomerization/intramolecular carbolithiation sequence is reported. This procedure provides an efficient, divergent, and straightforward entry to a wide range of polysubstituted dihydropyridines and pyridines starting from readily available N-allyl-ynamides.
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