Stereoselective alkylations of a bicyclic lactam derived from pyroglutamic acid

DOI: 10.1016/S0040-4039(99)00345-7

Source and publish data:

Tetrahedron Letters p. 2707 - 2710 (1999)

Update date:2022-07-29

Topics:

Authors:

Zhang, Rui

Brownewell, Floyd

Madalengoitia, Jose S.

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Article abstract of DOI:10.1016/S0040-4039(99)00345-7

Improvements in the stereoselective alkylation of a bicyclic lactam derived from pyroglutamic acid are described. This methodology is used to synthesize a conformationally constrained homo-glutamic acid analog.

Full text of DOI:10.1016/S0040-4039(99)00345-7

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