
Journal of Medicinal Chemistry p. 451 - 456 (1992)
Update date:2022-08-03
Topics:
Ocain
Rich
The design and synthesis of 3-amino-2-oxo-4-phenylbutanoic acid amides (α-keto amides), a new class of aminopeptidase inhibitor, are described. These compounds, illustrated by the Phe-Leu analogue 2, are effective inhibitors of arginyl aminopeptidase (K(i
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