Stereoselective synthesis of 3-fluoro azetidinones via the condensation of 2-fluoropropanethioate lithium enolate with imines

DOI: 10.1016/0040-4020(95)00869-A

Source and publish data:

Tetrahedron p. 255 - 262 (1996)

Update date:2022-08-04

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Authors:

Ishihara

Ichihara

Yamanaka

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Article abstract of DOI:10.1016/0040-4020(95)00869-A

S-Phenyl-2-fluoropropanethioate (1) was treated with lithium diisopropylamide in THF at -78°C to give rise to the lithium enolate, which underwent stereoselective condensation with a variety of aldehyde imines (2) at room temperature to afford the corresp

Full text of DOI:10.1016/0040-4020(95)00869-A

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Product name:2-Azetidinone, 3-fluoro-3-methyl-1,4-diphenyl-, trans-

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