Journal of Organic Chemistry p. 1514 - 1516 (1992)
Update date:2022-08-05
Topics:
Charlton, James L.
Koh, Kevin
A five-step asymmetric synthesis of neopodophyllotoxin in 18percent overall yield and optical purity >97percent, starting from 6-(3,4,5-trimethoxybenzyl)piperonal (6) and the fumarate of (S)-methyl mandelate (8), is described.
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Doi:10.1002/chir.22389
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