Phenanthrylalkanoic acids, V. A useful access to α-methylphenanthreneacetic acids

Article abstract of DOI:10.1002/ardp.2503241206

A very simple one-pot monomethylation of phenanthreneacetic acids 2 or of their methyl esters 1 yields α-methylphenanthreneacetic acids 3 in good yield. Alternatively, the process may be extended to the preparation of the corresponding α-arylisobutyric acids 4.