
Archiv der Pharmazie p. 967 - 969 (1991)
Update date:2022-09-26
Topics:
Balo
Fernandez
Gomez
Gonzalez
Lopez
A very simple one-pot monomethylation of phenanthreneacetic acids 2 or of their methyl esters 1 yields α-methylphenanthreneacetic acids 3 in good yield. Alternatively, the process may be extended to the preparation of the corresponding α-arylisobutyric acids 4.
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