
Chemical and Pharmaceutical Bulletin p. 2212 - 2215 (1991)
Update date:2022-07-29
Topics:
Konosu
Oida
The antifungal β-lactam (2R,5S)-2-(hydroxymethyl)clavam was synthesized in a convergent and stereocontrolled manner from methyl 6-phthalimidopenicillanate and 2,3-O-isopropylidene-(R)-glyceraldehyde. Convenient methods of acetonide cleavage and phthalimide deblocking are also described.
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Doi:10.1039/P19910002613
(1991)Doi:10.1021/ja00030a032
(1992)Doi:10.1016/S0040-4020(01)96212-X
(1991)Doi:10.1039/c8cc00058a
(2018)Doi:10.1124/dmd.111.041541
(2011)Doi:10.1021/acs.orglett.7b03917
(2018)