Nucleophilic Additions to and Reductions of 5-Formyl- and 5-Acyl-2-isoxazolines (4,5-Dihydroisoxazoles): A Stereoselective Route to β,γ-Dihydroxy Ketones

DOI: 10.1039/P19910002613

Source and publish data:

Journal of the Chemical Society. Perkin transactions I p. 2613 - 2625 (1991)

Update date:2022-07-29

Topics:

Authors:

Curran, Dennis P.

Zhang, Jiancun

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/P19910002613

Reductions of readily available 5-acyl-2-isoxazolines with L-Selectride follow the Felkin-Anh model and produce syn-5-hydroxyalkyl-2-isoxazolines with excellent (>95:5) selectivities.Swern oxidation of 5-hydroxymethyl-2-isoxazolines, followed by direct ad

Full text of DOI:10.1039/P19910002613

View Online / Journal Homepage / Table of Contents for this issue

View Online

Products guided by the article

Product name:trans-5-acetyl-4-methyl-3-phenyl-4,5-dihydroisoxazole

Cas No:138613-70-4

R&D Labs maybe for 138613-70-4

Shanghai agrotree chemical co.,ltd.

Contact:+86-21-50117563

Address:Room 8A,liangfeng building,No.8 dongfang RD.pudong,shanghai,China
Hunan Haili Chemical Industry Co.,Ltd.

Contact:+86-731-85521860

Address:No.251, 2nd Section, Furong Road, Changsha,Hunan,China
Xian Changyue Biological Technology Co., Ltd.

website:https://www.xachangyue.com/

Contact:+86-029-62886900

Address:Keji Road NO.70
Changsha Nutritopper Bio Technology Co.,Ltd.

Contact:+86-731-87803543

Address:East 1st Street, Baima Road, Ningxiang County
Meryer (Shanghai) Chemical Technology Co., Ltd.

website:http://www.meryer.com/cn/index/

Contact:+86-755-86170518

Address:Minhang,Shanghai, China

Relevant to this article

Synthesis and biological evaluation of benzothiazole derivatives bearing the ortho-hydroxy-N-acylhydrazone moiety as potent antitumor agents

Doi:10.1002/ardp.201400230
(2014)
Synthesis and anticonvulsant activity of some N-(benzoyl)glycinanilide derivatives

Doi:10.1007/s00044-013-0474-y
(2013)
A novel and high-yielding asymmetric synthesis of oseltamivir phosphate (Tamiflu) starting from (-)-shikimic acid

Doi:10.1016/j.tetasy.2012.05.014
(2012)
Expedient synthesis of 1-hydroxy-4- and 1-hydroxy-6-nitroindoles

Doi:10.1055/s-0031-1291044
(2012)
ENANTIOSELECTIVE SYNTHESIS OF FOUR ISOMERIC BUILDING BLOCKS USEFUL IN THE SYNTHESIS OF 2-NOR-LEUKOTRIENE ANALOGUES

Doi:10.1016/S0957-4166(00)80273-6
(1992)
Triplet states mediating hydrogen abstraction in 4-acylpyrimidines, 2-acylpyridines, 2-acylpyrazines, and 3-acylpyridazines

Doi:10.1021/ja00031a044
(1992)

Article Doi