Pyrazolo[3,4-d]pyrimidine analogues of isoguanine

Article abstract of DOI:10.1016/S0040-4039(00)93603-7

4-Amino-1-phenyl-5H-pyrazolo[3,4-d]pyrimidin-6-one (5a) was synthesized in 68% yield in a one pot reaction involving the condensation of 5-amino-1-phenylpyrazole-4-carbonitrile with benzoyl isocyanate followed by an annulation with ammonia.