
Tetrahedron Letters p. 6617 - 6620 (1991)
Update date:2022-08-04
Topics:
Chini
Crotti
Favero
Macchia
A simple, efficient, stereoselective, and highly regioselective method for the synthesis of β-hydroxyacetylenes by the direct opening of 1,2-epoxides with lithium acetylides in anhydrous THF, in the presence of metal salts, is described. This new method a
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