Heterocycles p. 2079 - 2082 (1991)
Update date:2022-08-04
Topics:
Tohda, Yasuo
Kawara, Tooru
Eiraku, Miyuki
Tani, Keita
Ariga, Masahiro
Mori, Yutaka
Regioselective synthesis of 2-substituted 3-nitropyridines was achieved by one-pot reaction of either 4- or 6-substituted 1-methyl-3,5-dinitro-2-pyridones with ketones in the presence of ammonia.The selectivity is interpreted in terms of steric factor of substituent on the pyridone.
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