Synthesis p. 1043 - 1045 (1991)
Update date:2022-07-29
Topics:
Micovic
Ivanovic
Piatak
Bojic
A simple and efficient method for the preparation of secondary N-alkylarylamines via reductive amination of ketones with primary aromatic amines using activated zinc/acetic acid is described. It requires only equimolar amounts of the starting compounds and affords good yields of the corresponding amines (50-90%). It is not applicable to aldehydes nor aliphatic amines.
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Doi:10.1021/jo301300b
(2012)Doi:10.1007/s10600-012-0258-5
(2012)Doi:10.1007/BF00958008
(1991)Doi:10.1007/BF00778981
(1991)Doi:10.1016/j.tet.2016.04.068
(2016)Doi:10.1021/ja301872s
(2012)
