Development and evaluation of multifunctional agents for potential treatment of Alzheimer's disease: Application to a pyrimidine-2,4-diamine template

DOI: 10.1016/j.bmcl.2012.05.077

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 4707 - 4712 (2012)

Update date:2022-08-05

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Authors:

Mohamed, Tarek

Yeung, Jacky C.K.

Vasefi, Maryam S.

Beazely, Michael A.

Rao, Praveen P.N.

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Article abstract of DOI:10.1016/j.bmcl.2012.05.077

We investigated a group of 2-benzylpiperidin-N-benzylpyrimidin-4-amines with various electron-withdrawing or electron-donating groups (EWGs or EDGs, respectively) as multi-targeted Alzheimer's disease (AD) therapeutics. The synthesized derivatives were sc

Full text of DOI:10.1016/j.bmcl.2012.05.077

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