Synthesis of 3,4-Disubstituted Pyrroles Bearing Substituents of Electron-Withdrawing and/or Electron-Donating Nature

DOI: 10.1021/jo00034a011

Source and publish data:

Journal of Organic Chemistry p. 2245 - 2249 (1992)

Update date:2022-08-03

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Authors:

Leusen, Daan van

Echten, Erik van

Leusen, Albert M. van

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Article abstract of DOI:10.1021/jo00034a011

The synthesis is described of a series of 3,4-disubstituted pyrroles 8 from 1-isocyano-1-tosyl-1-alkenes and a variety of Michael donors.It is possible to use this method for the synthesis of pyrroles that bear no electron-withdrawing substituents.

Full text of DOI:10.1021/jo00034a011

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